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Regarding editing SMAclAccess.ini, the following notice is mentioned in article #KB0090343.
"Only edit the SMAclAccess.ini file when no Domino processes are running."
Standalone Domino processes may fail to start on Microsoft Windows
https://support.hcltechsw.com/csm?id=kb_article&sysparm_article=KB0090343
It want to be able to edit SMAclAccess.ini by "set conf" command in Domino server dynamically as notes.ini file.
If it will be able to do by that way, Domino Administrator will not need to restart the Domino server every time they change SMAclAccess.ini file.
This is a security feature which requires to restart the server. Not possible to implement your idea.