It would be nice to have the possibility to configure NRPC to use a different TCP port than 1352.
Moving NRPC to a different than the default port would make finding Domino services - a little bit - harder for those mass-port-scanners in the net.
Also it would be a way to circumvent hotel WLANs, guest WLANs in businesses or other public hotspots that block all not well-known TCP ports. Exposing Domino on a well-known port should make connections from these WLANs still be possible.
On the server side in most cases you will have a firewall in front on Domino. There you might use port-mapping to route incoming traffic on the non-default port to the default port internally.
But you still would need an option to tell the Notes client to connect to this port instead of 1352.